TPSTHIGH SIGNALFINANCIAL10-K

TPST experienced severe financial deterioration with cash declining 75% to just $7.7M while simultaneously executing a reverse stock split that reduced share count from 45.4M to 14.3M shares.

The dramatic cash burn combined with a reverse stock split signals acute financial distress and potential going concern issues for this clinical-stage biotech company. While the company pivoted strategy by acquiring CAR-T assets in February 2026, the severely constrained cash position raises immediate questions about their ability to fund operations and clinical development without emergency financing.

Comparing 2026-03-30 vs 2025-03-27View on EDGAR →
FINANCIAL ANALYSIS

TPST's financial position deteriorated dramatically with cash and equivalents plummeting 75% from $30.3M to $7.7M, while total assets declined 59% and stockholders' equity fell 65%. Although net losses improved 37% to -$26.3M due to reduced SG&A expenses (-44%), and revenue declined 55%, the company's cash runway appears critically short for a clinical-stage biotech requiring substantial R&D funding. The massive reduction in current assets (-74%) alongside the reverse stock split indicates severe liquidity constraints that could threaten ongoing operations.

FINANCIAL STATEMENT CHANGES
Current Liabilities
Balance Sheet
-76.7%
$14.2M$3.3M

Current liabilities reduced — improved short-term financial position and working capital health.

Cash & Equivalents
Balance Sheet
-74.5%
$30.3M$7.7M

Cash declined 74.5% — significant cash burn or deployment; verify adequacy of remaining liquidity runway.

Current Assets
Balance Sheet
-73.7%
$31.5M$8.3M

Current assets declined 73.7% — monitor working capital adequacy and short-term liquidity.

Stockholders Equity
Balance Sheet
-65.1%
$19.1M$6.7M

Equity declined sharply — large losses, buybacks, or write-downs reducing book value significantly.

Total Assets
Balance Sheet
-59.2%
$41.5M$16.9M

Total assets contracted 59.2% — asset sales, write-downs, or balance sheet optimization underway.

Revenue
P&L
-54.8%
$653K$295K

Revenue declined 54.8% — significant demand weakness or market share loss warrants investigation.

Total Liabilities
Balance Sheet
-54.1%
$22.4M$10.3M

Liabilities reduced 54.1% — deleveraging improves balance sheet strength and financial flexibility.

SG&A Expense
P&L
-43.6%
$49.2M$27.7M

SG&A reduced 43.6% — improved cost efficiency or headcount reduction improving operating margins.

Total Debt
Balance Sheet
-39%
$10.5M$6.4M

Debt reduced 39% — deleveraging strengthens balance sheet and reduces financial risk.

Net Income
P&L
+37.2%
-$41.8M-$26.3M

Net income grew 37.2% — bottom-line growth signals improving overall business health.

LANGUAGE CHANGES
NEW — 2026-03-30
PRIOR — 2025-03-27
ADDED
As of March 25, 2026, the registrant had 14,344,034 shares of common stock, $0.001 par value per share, outstanding.
BUSINESS Overview We are a clinical-stage biotechnology company advancing a diversified portfolio of cell therapy and small molecule product candidates.
In February 2026, we expanded our pipeline through a strategic transaction under which we acquired rights to a portfolio of dual-targeting chimeric antigen receptor T-cells ( CAR-T ) product candidates with the potential to treat certain blood cancers, solid tumors and immunology indications, including TPST-2003, an autologous CD19/B-cell maturation antigen ( BCMA ) CAR-T therapy currently in clinical development for relapsed or refractory multiple myeloma ( rrMM ).
Our portfolio also includes two clinical-stage small molecule product candidates with the potential to treat certain cancer indications.
One of our small-molecule product candidates, amezalpat (previously known as TPST-1120), has completed a Phase 2 study in first-line hepatocellular carcinoma ( HCC ).
+7 more — sign up free →
REMOVED
As of March 21, 2025, the registrant had 45,483,384 shares of common stock, $0.001 par value per share, outstanding.
BUSINESS Overview We are a clinical-stage biotechnology company moving towards late-stage development with a diverse portfolio of targeted and immune-mediated product candidates with the potential to be first-in-class to treat a wide range of cancers.
Our novel programs range from early research to the lead program, amezalpat (previously known as TPST-1120), that is poised to begin a pivotal study in first-line hepatocellular carcinoma ( HCC ).
In addition to amezalpat, our second clinical-stage therapeutic product candidate is TPST-1495, which we expect will enter Phase 2 development in 2025.
Our philosophy is to build a company based upon not only good ideas and creative science, but also upon the efficient translation of those ideas into therapies that will improve patients lives.
+7 more — sign up free →
MORE FINANCIAL SIGNALS
PNRGHIGHPNRG achieved exceptional profitability improvement with net income surging 2,21...
2026-04-16
BNAIHIGHBNAI underwent a dramatic reverse stock split that reduced share count by 86% wh...
2026-04-16
LAKEHIGHLAKE's financial performance deteriorated significantly with operating losses wo...
2026-04-16
NXXTHIGHNextNRG experienced massive financial deterioration with operating losses explod...
2026-04-16
ANALYZE ANY FILING FREE

See what changed in your portfolio's filings

500+ US-listed companies analyzed. Language delta, financial analysis, instant signal scoring.

Try Tracenotes free →