TGTXHIGH SIGNALFINANCIAL10-K

TGTX's balance sheet roughly doubled in total assets while revenue declined substantially and operating expenses expanded meaningfully, signaling a company in aggressive commercial build-out mode with deteriorating near-term fundamentals.

Revenue declined substantially year-over-year (from $6.7M to $2.8M), which is a material negative signal for a company that appears to be in early commercialization — suggesting product ramp is not yet offsetting base revenue erosion. Cash and equivalents fell by more than half (from $179.9M to $79.1M), a concrete liquidity trigger, even as total assets grew to $1.1B — implying the asset base expansion is being driven by non-cash items rather than cash generation. Investors should closely monitor the company's cash runway given the combination of declining cash, expanding cost structure, and negative operating cash flow, even though operating cash burn improved modestly to -$24.8M.

Comparing 2026-02-27 vs 2025-03-03View on EDGAR →
FINANCIAL ANALYSIS

TGTX's cost structure expanded substantially across both R&D (from $94.3M to $160.2M, roughly +70%) and SG&A (from $154.3M to $232.0M, up approximately 50%), reflecting a company scaling commercial and development infrastructure simultaneously. Total assets grew meaningfully to $1.1B and total debt rose modestly to $100.4M (+41.1%), while current liabilities grew notably to $153.8M — indicating the balance sheet is being leveraged to fund operations. The overall picture is one of a pre-profitability biotech absorbing heavy investment-phase costs against a shrinking revenue base, with cash declining sharply; the key investor question is whether the commercial asset base will generate sufficient future revenue to justify the current spending trajectory before cash reserves require replenishment.

FINANCIAL STATEMENT CHANGES
Total Assets
Balance Sheet
+84.1%
$577.7M$1.1B

Asset base grew 84.1% — expansion through organic growth, acquisitions, or capital deployment.

R&D Expense
P&L
+69.9%
$94.3M$160.2M

R&D investment increased 69.9% — signals commitment to future product development, though near-term margin impact.

Current Liabilities
Balance Sheet
+69.6%
$90.7M$153.8M

Current liabilities surged 69.6% — significant near-term obligations; verify ability to meet short-term debt.

Revenue
P&L
-58.4%
$6.7M$2.8M

Revenue declined 58.4% — significant demand weakness or market share loss warrants investigation.

Cash & Equivalents
Balance Sheet
-56%
$179.9M$79.1M

Cash declined 56% — significant cash burn or deployment; verify adequacy of remaining liquidity runway.

SG&A Expense
P&L
+50.4%
$154.3M$232.0M

SG&A up 50.4% — significant increase in sales or administrative costs, monitor impact on operating leverage.

Total Debt
Balance Sheet
+41.1%
$71.1M$100.4M

Debt increased 41.1% — substantial leverage increase; assess whether deployed for growth or covering losses.

Operating Cash Flow
Cash Flow
+38.9%
-$40.5M-$24.8M

Operating cash flow surged 38.9% — exceptional cash generation, highest quality earnings signal.

Interest Expense
P&L
+23.8%
$10.2M$12.6M

Interest costs rose 23.8% — monitor debt levels and coverage ratio in rising rate environment.

Total Liabilities
Balance Sheet
+16.9%
$355.3M$415.2M

Liabilities increased 16.9% — monitor debt-to-equity ratio and interest coverage.

LANGUAGE CHANGES
NEW — 2026-02-27
PRIOR — 2025-03-03
ADDED
false --12-31 FY 2025 true true true false The Board receives regular reports from our Chief Executive Officer, Chief Financial Officer and other members of management, regarding material cybersecurity threats and risks, effectiveness of our information security processes and status of ongoing cybersecurity initiatives and strategies.
Our information technology (IT) team, which is overseen by our Vice President of IT, is responsible for the identification, assessment and management of cybersecurity risks we face and ensuring effective implementation of the Company s overall cybersecurity efforts.
Our Vice President of IT has over 25 years of experience in IT systems, including cybersecurity risk management and incident response, and holds multiple industry-recognized certifications.
Our Vice President of IT receives regular reports from the corporate IT Security Team, together with information provided by our third-party service organizations that support monitoring of aspects of the Company s IT environment, regarding the Company s material cybersecurity threats and risks and the processes the Company has implemented to address them, which information is reported, as appropriate, to the Chief Financial Officer.
The Board receives regular reports from our Chief Executive Officer, Chief Financial Officer and other members of management, regarding material cybersecurity threats and risks, effectiveness of our information security processes and status of ongoing cybersecurity initiatives and strategies.
Our information technology (IT) team, which is overseen by our Vice President of IT, is responsible for the identification, assessment and management of cybersecurity risks we face and ensuring effective implementation of the Company s overall cybersecurity efforts.
Our Vice President of IT has over 25 years of experience in IT systems, including cybersecurity risk management and incident response, and holds multiple industry-recognized certifications.
Our Vice President of IT receives regular reports from the corporate IT Security Team, together with information provided by our third-party service organizations that support monitoring of aspects of the Company s IT environment, regarding the Company s material cybersecurity threats and risks and the processes the Company has implemented to address them, which information is reported, as appropriate, to the Chief Financial Officer.
The Board receives regular reports from our Chief Executive Officer, Chief Financial Officer and other members of management, regarding material cybersecurity threats and risks, effectiveness of our information security processes and status of ongoing cybersecurity initiatives and strategies.
Our information technology (IT) team, which is overseen by our Vice President of IT, is responsible for the identification, assessment and management of cybersecurity risks we face and ensuring effective implementation of the Company s overall cybersecurity efforts.
REMOVED
false --12-31 FY 2024 true true true false true true false false false false 0.001 0.001 190,000,000 175,000,000 156,204,159 151,465,598 155,836,256 151,424,289 367,903 41,309 800 1.3 January 1, 2025 December 31, 2025 January 1, 2023 December 31, 2023 0 0 5 0 7 7 7 4.6 1 5 5 5 10.04 21 21 2021 2022 2023 2024 0 0.2 0.2 2 As our leases do not provide an implicit rate, we use our incremental borrowing rate based on the information available at commencement date and considering the term of the lease to determine the present value of lease payments.
We used an incremental borrowing rate of 5.65% for the NC lease.
Amounts as of December 31, 2023 have been reclassified to conform to current period presentation.
There were 157,070,575 shares of the registrant s common stock, $0.001 par value, outstanding as of February 25, 2025.
In addition, with respect to all of our forward-looking statements, we claim the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995.
You should carefully consider these risks, the risk factors discussed in the section entitled Risk Factors in Part I, Item 1A of this Annual Report on Form 10-K, and any other risks described in the other reports and documents that we have filed with the Securities and Exchange Commission (SEC).
Food and Drug Administration (FDA) or European Medicines Agency (EMA) approval for a product candidate and do not achieve broad market acceptance among physicians, patients, healthcare payors, and the medical community, the revenues that we generate from product sales will be limited.
The incidence and prevalence for target patient populations of BRIUMVI and our product candidates, including azer-cel in non-oncology indications, have not been established with precision.
Risks Related to our Financial Position and Need for Additional Capital While we have recently generated net income, we have incurred significant operating losses since our inception, and we may incur losses in the future.
If we fail to comply with various healthcare laws and regulations, we may incur losses or be subject to liability.
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