RNXTMEDIUM SIGNALOPERATIONAL10-K

RNXT has shifted from a dual clinical-stage/commercial-stage positioning to focus primarily on commercializing its FDA-cleared RenovoCath device while expanding its business description to emphasize "developing innovative targeted oncology therapies."

The removal of specific clinical-stage language and the IAG drug-device combination candidate suggests a strategic pivot toward near-term commercialization revenue rather than expensive clinical development. However, the share count increase from 36.5M to 45.1M shares indicates likely dilutive financing, which investors should monitor for terms and use of proceeds.

Comparing 2026-03-30 vs 2025-04-01View on EDGAR →
FINANCIAL ANALYSIS

RNXT's financial position shows mixed signals with operating losses deepening as net income declined to -$11.2M from -$8.8M and operating cash flow worsening to -$11.0M. However, the balance sheet strengthened with stockholders' equity growing 21% to $5.4M and total liabilities decreasing 27% to $2.7M, suggesting recent capital raising activity that improved the company's financial foundation despite ongoing operational burn.

FINANCIAL STATEMENT CHANGES
Capital Expenditure
Cash Flow
-83.3%
$12K$2K

Capex reduced 83.3% — investment cycle winding down or capital discipline; may improve near-term free cash flow.

SG&A Expense
P&L
+41.1%
$5.0M$7.0M

SG&A up 41.1% — significant increase in sales or administrative costs, monitor impact on operating leverage.

Net Income
P&L
-26.7%
-$8.8M-$11.2M

Net income declined 26.7% — review whether driven by operations, interest costs, or non-recurring items.

Total Liabilities
Balance Sheet
-26.6%
$3.6M$2.7M

Liabilities reduced 26.6% — deleveraging improves balance sheet strength and financial flexibility.

Stockholders Equity
Balance Sheet
+21.1%
$4.5M$5.4M

Equity base grew 21.1% — retained earnings accumulation or equity issuance strengthening the balance sheet.

Operating Cash Flow
Cash Flow
-20.3%
-$9.1M-$11.0M

Operating cash flow softened — monitor whether temporary working capital timing or structural deterioration.

Operating Income
P&L
-14%
-$11.0M-$12.5M

Operating profitability softening — costs rising faster than revenue, watch for margin recovery plan.

LANGUAGE CHANGES
NEW — 2026-03-30
PRIOR — 2025-04-01
ADDED
The number of outstanding shares of the registrant s common stock, $ 0.0001 par value per share, as of March 23,2026, was 45,052,706 .
BUSINESS Overview We are a life sciences company developing innovative targeted oncology therapies and commercializing RenovoCath , a novel, U.S.
Food and Drug Administration ( FDA )-cleared local drug-delivery device, targeting high unmet medical needs.
Our mission is to transform the lives of cancer patients by providing innovative solutions to enable targeted delivery of therapeutic agents.
Our patented Trans-Arterial Micro-Perfusion (TAMP ) therapy platform, enabled by RenovoCath, is designed for targeted therapeutic delivery across the arterial wall near the tumor site (known as intra-arterial , or IA delivery) to bathe the target tumor, while potentially minimizing a therapy s toxicities versus systemic intravenous therapy.
We are actively commercializing the TAMP therapy platform and RenovoCath as a stand-alone device within its FDA cleared fields of use.
We are a commercial-stage growth company commercializing RenovoCath in the United States, have received our first commercial purchase orders for RenovoCath devices in December 2024.
For the year ended December 31, 2025, we generated an aggregate of $1.1 million in revenue from RenovoCath sales.
cancer centers that initiated repeat orders as well as new institutions adopting the device, including several esteemed, high-volume National Cancer Institute-designated centers.
While we strive to meet and satisfy the anticipated demand, we continue to actively explore further revenue-generating activity, either on our own or in tandem with a medical device commercial partner.
REMOVED
The number of outstanding shares of the registrant s common stock, $ 0.0001 par value per share, as of March 25, 2025, was 36,546,752 .
BUSINESS Overview We are a life sciences company offering RenovoCath , a novel, U.S.
Food and Drug Administration ( FDA )-cleared local drug-delivery device, targeting high unmet medical needs, with a present focus on difficult to treat cancers.
Our mission is to transform the lives of cancer patients by providing innovative solutions to enable targeted therapeutic delivery.
We are both a clinical stage and a commercial stage enterprise.
Our clinical stage lead product candidate is a novel drug-device combination product consisting of intra-arterial delivery of the chemotherapy gemcitabine via RenovoCath -- we refer to our lead product candidate herein as IAG .
IAG is currently the subject of a pivotal Phase III clinical study for the treatment of locally advanced pancreatic cancer ( LAPC ).
At the same time, we are commercializing RenovoCath for standalone use by interventional radiologists, oncologists and other medical professionals who can use RenovoCath to treat patients within its FDA-cleared fields of use.
RenovoCath utilizes our patented Trans-Arterial Micro-Perfusion (TAMP ) therapy platform, which is designed to ensure precise therapeutic delivery across the arterial wall near the target tumor site to bathe the tumor, while potentially minimizing a therapy s toxicities versus systemic intravenous (or IV) therapy, including traditional chemotherapy.
For the past several years, we have focused our efforts on progressing IAG through clinical trials.
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