PGENHIGH SIGNALFINANCIAL10-K

PGEN shows severe financial deterioration with net losses doubling to $251M, interest expense exploding 1,296%, and stockholders' equity declining 46% while transitioning from going concern warnings to dependence on commercial success of newly named drug Papzimeos.

The dramatic shift from going concern language to commercial dependence messaging, combined with a massive 60M share increase, suggests PGEN may have secured financing or partnership tied to their lead asset (formerly PRGN-2012, now Papzimeos). However, the explosion in interest expense and liabilities indicates this capital came at a very high cost, creating substantial financial risk.

Comparing 2026-03-25 vs 2025-03-19View on EDGAR →
FINANCIAL ANALYSIS

PGEN's financials show severe stress with net losses doubling to $251M driven by 1,296% surge in interest expense to $8.5M and 70% increase in SG&A expenses, while R&D spending declined 22%. The balance sheet deteriorated significantly with total liabilities jumping 71% to $135M, stockholders' equity falling 46% to $21M, and operating cash burn worsening 29% to $88M. The combination of exploding debt service costs, shrinking equity cushion, and worsening cash burn creates a precarious financial position despite the apparent influx of capital suggested by the 60M share increase.

FINANCIAL STATEMENT CHANGES
Interest Expense
P&L
+1296.1%
$611K$8.5M

Interest expense surged 1296.1% — significant debt increase or rising rates materially impacting earnings.

Accounts Receivable
Balance Sheet
+322.9%
$926K$3.9M

Receivables surged 322.9% — revenue recognized but not yet collected; watch for collection issues or channel stuffing.

Net Income
P&L
-98.6%
-$126.2M-$250.6M

Net income declined 98.6% — review whether driven by operations, interest costs, or non-recurring items.

Capital Expenditure
Cash Flow
-76.8%
$8.6M$2.0M

Capex reduced 76.8% — investment cycle winding down or capital discipline; may improve near-term free cash flow.

Current Liabilities
Balance Sheet
+73.4%
$21.5M$37.3M

Current liabilities surged 73.4% — significant near-term obligations; verify ability to meet short-term debt.

Total Liabilities
Balance Sheet
+71.4%
$78.5M$134.6M

Liabilities grew 71.4% — significant increase in debt or obligations, assess impact on financial flexibility.

SG&A Expense
P&L
+69.8%
$41.3M$70.1M

SG&A up 69.8% — significant increase in sales or administrative costs, monitor impact on operating leverage.

Stockholders Equity
Balance Sheet
-45.7%
$38.5M$20.9M

Equity declined sharply — large losses, buybacks, or write-downs reducing book value significantly.

Operating Cash Flow
Cash Flow
-28.8%
-$68.2M-$87.8M

Operating cash flow softened — monitor whether temporary working capital timing or structural deterioration.

R&D Expense
P&L
-22.1%
$53.1M$41.3M

R&D spending cut 22.1% — could signal cost discipline or concerning reduction in innovation investment.

LANGUAGE CHANGES
NEW — 2026-03-25
PRIOR — 2025-03-19
ADDED
As of February 15, 2026, 353,928,672 shares of common stock, no par value per share, were issued and outstanding.
Management's Discussion and Analysis of Financial Condition and Results of Operations 73 Item 7A.
Form 10-K Summary 91 ________________________ Precigen , AdenoVerse , UltraCAR-T , RheoSwitch , UltraVector , RTS , UltraPorator , ActoBiotics , Advancing Medicine With Precision , RRP Awareness Day , Giving Voice to Inspire Change , and RheoSwitch Therapeutic System are our and/or our affiliates' registered trademarks in the United States and GenVec , Papzimeos , Recurrent Respiratory Papillomatosis Awareness Giving Voice to Inspire Change , RRP Awareness Design , and RRP Awareness Day Giving Voice to Inspire Change are our and/or our affiliates' common law trademarks in the United States.
Risks Related to Our Financial Position and Capital Needs We are substantially dependent on the commercial success of Papzimeos.
Our level of indebtedness and debt service obligations could adversely affect our financial condition and may make it more difficult for us to fund our operations.
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REMOVED
As of February 15, 2025, 294,042,973 shares of common stock, no par value per share, were issued and outstanding.
Management's Discussion and Analysis of Financial Condition and Results of Operations 70 Item 7A.
Risks Related to Our Financial Position and Capital Needs We will need substantial additional capital in the future in order to fund our business and have identified conditions that raise substantial doubt about our ability to continue as a going concern.
We have a limited number of shares of common stock available for future issuance which could adversely affect our ability to raise capital or consummate strategic transactions.
Our strategic prioritization and streamlining of resources undertaken to extend our cash runway and focus more of our capital resources on PRGN-2012 might not achieve our intended outcome.
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