CYRXMEDIUM SIGNALOPERATIONAL10-K

CYRX completed the CRYOPDP divestiture while substantially improving operating performance despite lower revenue.

The company appears to be executing a strategic refocusing around its core cell and gene therapy market, as evidenced by the divestiture and updated business description emphasizing CGT specialization. The meaningful improvement in operating losses alongside reduced SG&A expenses suggests management is successfully rightsizing the business post-divestiture.

Comparing 2026-03-05 vs 2025-03-07View on EDGAR →
FINANCIAL ANALYSIS

Revenue declined 23% to $176.2M, likely reflecting the CRYOPDP divestiture impact, but the company achieved substantially better operating performance with losses narrowing meaningfully from the prior year. Strong balance sheet improvements include 39% growth in current assets and 25% increase in stockholders' equity, while total liabilities decreased 13%, indicating improved financial positioning. The reduced share buyback activity from $38M to $10M suggests management is prioritizing capital preservation during this transition period.

FINANCIAL STATEMENT CHANGES
Share Buybacks
Cash Flow
-73.6%
$38.0M$10.0M

Buyback activity reduced 73.6% — capital being redeployed elsewhere or cash conservation underway.

Operating Income
P&L
+71.9%
-$130.9M-$36.8M

Operating leverage kicking in — revenue growth outpacing cost growth, a hallmark of scaling businesses.

Operating Cash Flow
Cash Flow
+47.4%
-$16.3M-$8.6M

Operating cash flow surged 47.4% — exceptional cash generation, highest quality earnings signal.

Current Assets
Balance Sheet
+39.4%
$341.6M$476.2M

Current assets grew 39.4% — improving short-term liquidity or inventory/receivables build.

SG&A Expense
P&L
-31%
$149.0M$102.8M

SG&A reduced 31% — improved cost efficiency or headcount reduction improving operating margins.

Accounts Receivable
Balance Sheet
-27.1%
$45.8M$33.4M

Receivables declined — improved collection efficiency or conservative revenue recognition.

Stockholders Equity
Balance Sheet
+25.1%
$401.9M$502.6M

Equity base grew 25.1% — retained earnings accumulation or equity issuance strengthening the balance sheet.

Revenue
P&L
-22.9%
$228.4M$176.2M

Revenue softened 22.9% — monitor whether this is cyclical or structural.

Gross Profit
P&L
-16.6%
$99.6M$83.1M

Gross margin compression — rising input costs, pricing pressure, or unfavorable product mix shift.

Total Liabilities
Balance Sheet
-13%
$301.6M$262.4M

Liabilities reduced 13% — deleveraging improves balance sheet strength and financial flexibility.

LANGUAGE CHANGES
NEW — 2026-03-05
PRIOR — 2025-03-07
ADDED
As of February 27, 2026, there were 49,856,135 shares of the registrant s common stock outstanding.
Additional risks and uncertainties relating to the CRYOPDP divestiture include the risk that any disruption resulting from the CRYOPDP divestiture may adversely affect our businesses and business relationships, including with employees and suppliers.
Business Overview We are a leading global provider of integrated, temperature-controlled supply chain solutions for the life sciences, with a strong focus on supporting the rapidly growing cell and gene therapy ( CGT ) market.
Our solutions are purpose-built to support a broad range of global life sciences markets, including biopharmaceutical and pharmaceutical companies, the animal health markets, reproductive medicine, academic institutions, research, and government agencies.
Our solutions help our customers ensure the safe, compliant storage, handling, and delivery of high value, temperature sensitive biological materials, including cell and gene therapies and immunotherapies.
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REMOVED
As of February 28, 2025, there were 49,910,391 shares of the registrant s common stock outstanding.
Business Overview We are global leader in integrated temperature-controlled supply chain solutions for the life sciences industry, with a strong focus on supporting the Cell and Gene Therapy market (CGT).
Our broad array of products and services are designed to mitigate risks and ensure the safe and reliable storage and delivery of critical therapies and other high value biologic materials.
We support the entire continuum from biomaterial collection to final delivery, Enabling the Future of Medicine TM .
Our integrated supply chain platform leverages advanced temperature-controlled packaging, systems, and informatics to deliver essential solutions for companies in the CGT ecosystem, including: BioLogistics services BioStorage/BioServices Cryopreservation services Cryogenic systems We have a market leading role in supporting the CGT market and other markets in the life sciences industry that require comprehensive, technology-centric supply chain solutions for high-value products and materials.
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