CRSPHIGH SIGNALFINANCIAL10-K

CRISPR Therapeutics shows substantially deteriorating financial performance with meaningfully higher net losses despite reduced R&D spending, while increasing share count suggests significant equity financing.

The company's financial position has weakened considerably with operating losses expanding substantially even as R&D expenses declined, suggesting either increased costs in other areas or reduced collaboration revenues. The notable increase in outstanding shares from 85.8M to 96.0M indicates the company likely raised capital through equity financing, which was necessary given the higher cash burn rate.

Comparing 2026-02-12 vs 2025-02-11View on EDGAR →
FINANCIAL ANALYSIS

CRISPR's financial picture reflects a challenging period with net losses expanding substantially to $581.6M despite an 11.2% reduction in R&D expenses to $284.8M, indicating pressure from other cost categories or reduced revenues. Current liabilities increased notably to $149.1M, though cash and equivalents grew modestly to $347.6M. The 12% increase in share count combined with higher losses suggests the company accessed equity markets to fund operations amid accelerating cash consumption.

FINANCIAL STATEMENT CHANGES
Current Liabilities
Balance Sheet
+69.9%
$87.8M$149.1M

Current liabilities surged 69.9% — significant near-term obligations; verify ability to meet short-term debt.

Net Income
P&L
-58.8%
-$366.3M-$581.6M

Net income declined 58.8% — review whether driven by operations, interest costs, or non-recurring items.

Capital Expenditure
Cash Flow
-51.9%
$1.9M$914K

Capex reduced 51.9% — investment cycle winding down or capital discipline; may improve near-term free cash flow.

Operating Income
P&L
-42.4%
-$466.6M-$664.6M

Operating income deteriorated sharply — investigate whether driven by one-time charges or structural cost issues.

Cash & Equivalents
Balance Sheet
+16.5%
$298.3M$347.6M

Cash grew 16.5% — improving liquidity position supports investment and shareholder returns.

R&D Expense
P&L
-11.2%
$320.7M$284.8M

R&D spending cut 11.2% — could signal cost discipline or concerning reduction in innovation investment.

Total Liabilities
Balance Sheet
+10.8%
$310.0M$343.4M

Liabilities increased 10.8% — monitor debt-to-equity ratio and interest coverage.

LANGUAGE CHANGES
NEW — 2026-02-12
PRIOR — 2025-02-11
ADDED
The number of the Registrant s common shares outstanding as of February 10, 2026 was 95,985,312 .
CRISPR Therapeutics standard character mark and design logo, CRISPRX , CRISPR TX , CTX112 , CTX211 , CTX213 , CTX310 , CTX321 , CTX340 , CTX460 , CTX611 and SyNTase are trademarks and registered trademarks of CRISPR Therapeutics AG.
governmental agencies, new or increased international tariffs and retaliatory tariffs, interest rate and currency rate fluctuations, new laws and regulations or amendments to existing laws and regulations in the U.S.
and foreign countries, trade protection measures, economic sanctions and economic slowdowns or recessions, banking instability, monetary policy changes, geopolitical tensions or the outbreak of hostilities or war.
We are a leading biopharmaceutical company focused on the development of CRISPR-based therapeutics, including by using CRISPR/Cas9 technology.
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REMOVED
The number of the Registrant s common shares outstanding as of February 7, 2025 was 85,774,474 .
CRISPR Therapeutics standard character mark and design logo, CRISPRX TM , CRISPR TX TM , CTX112 TM , CTX131 TM , CTX211 TM , CTX213 TM , CTX310 TM , CTX320 TM , CTX330 TM , CTX340 TM , and CTX450 TM , are trademarks and registered trademarks of CRISPR Therapeutics AG.
We are a leading gene editing company focused on the development of CRISPR-based therapeutics, including by using CRISPR/Cas9 technology.
We aim to apply this technology to disrupt, delete, correct and insert genes to treat genetic diseases and to engineer advanced cellular therapies.
The use of CRISPR/Cas9 for gene editing was co-invented by one of our scientific founders, Dr.
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