CDNAHIGH SIGNALFINANCIAL10-K

CareDx experienced dramatic financial volatility with revenue surging 296% while simultaneously swinging from $52.5M net income to -$21.4M loss, coupled with aggressive $87.8M share buybacks despite burning through $49M in cash.

The company appears to be in a rapid growth phase but at significant cost to profitability, suggesting either major operational challenges or strategic investments that haven't yet paid off. The massive share buyback program while burning cash and posting losses raises questions about capital allocation strategy and management's confidence in the business trajectory.

Comparing 2026-02-25 vs 2025-02-28View on EDGAR →
FINANCIAL ANALYSIS

CareDx delivered exceptional revenue growth of 296% to $48.3M with gross profit nearly doubling, indicating strong market demand for their precision medicine solutions. However, the company simultaneously experienced a dramatic profitability collapse, swinging from $52.5M net income to -$21.4M loss, while cash reserves dropped 43% to $65.4M and debt increased 42%. The aggressive $87.8M share buyback program during a loss-making period, combined with significant increases in capital expenditure and inventory buildup, suggests the company is investing heavily for future growth while prioritizing shareholder returns despite current operational challenges.

FINANCIAL STATEMENT CHANGES
Share Buybacks
Cash Flow
+16713.8%
$522K$87.8M

Share repurchases increased 16713.8% — management returning capital, signals confidence in intrinsic value.

Capital Expenditure
Cash Flow
+994.1%
$186K$2.0M

Capital expenditure jumped 994.1% — major investment cycle underway; assess returns on deployment.

Revenue
P&L
+296.4%
$12.2M$48.3M

Strong top-line growth of 296.4% — accelerating demand or successful expansion into new markets.

Operating Income
P&L
-175.5%
$40.8M-$30.8M

Operating income deteriorated sharply — investigate whether driven by one-time charges or structural cost issues.

Net Income
P&L
-140.6%
$52.5M-$21.4M

Net income declined 140.6% — review whether driven by operations, interest costs, or non-recurring items.

Gross Profit
P&L
+87.3%
$43.6M$81.6M

Gross profit expanding — improving pricing power or product mix shift toward higher-margin offerings.

Cash & Equivalents
Balance Sheet
-43%
$114.7M$65.4M

Cash declined 43% — significant cash burn or deployment; verify adequacy of remaining liquidity runway.

Total Debt
Balance Sheet
+42.2%
$23.9M$34.1M

Debt increased 42.2% — substantial leverage increase; assess whether deployed for growth or covering losses.

Inventory
Balance Sheet
+36.9%
$19.5M$26.7M

Inventory surged 36.9% — growing faster than typical sales pace; potential demand softening or supply chain overcorrection.

Accounts Receivable
Balance Sheet
-34%
$64.6M$42.6M

Receivables declined — improved collection efficiency or conservative revenue recognition.

LANGUAGE CHANGES
NEW — 2026-02-25
PRIOR — 2025-02-28
ADDED
The aggregate market value of the voting and non-voting common equity held by non-affiliates of the registrant, based on the closing price of a share of the registrant s common stock on June 30, 2025, the last business day of the registrant s most recently completed second fiscal quarter, as reported by the Nasdaq Global Market on such date was approximately $ 1.0 billion.
You should not rely upon forward-looking statements as predictions of future events.
BUSINESS Company Overview CareDx is a precision medicine company dedicated to improving outcomes for transplant patients and advancing organ health.
We deliver solutions designed to empower clinicians and improve patient outcomes.
The Company's integrated solutions include non-invasive molecular testing for heart, kidney, and lung transplants; laboratory products; digital health technologies; and patient solutions that support care before and after transplant.
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REMOVED
The aggregate market value of the voting and non-voting common equity held by non-affiliates of the registrant, based on the closing price of a share of the registrant s common stock on June 28, 2024, the last business day of the registrant s most recently completed second fiscal quarter, as reported by the Nasdaq Global Market on such date was approximately $ 772.5 million.
You should read this Annual Report on Form 10-K and the documents that we reference in this Annual Report on Form 10-K and have filed with the Securities and Exchange Commission, or the SEC, as exhibits to this Annual Report on Form 10-K with the understanding that our actual future results, levels of activity, performance and events and circumstances may be materially different from what we expect.
BUSINESS Company Overview CareDx is a leading precision medicine company focused on the discovery, development and commercialization of clinically differentiated, high-value diagnostic solutions for transplant patients and caregivers.
We offer testing services, products, and patient and digital solutions along the pre- and post-transplant patient journey, and we are a leading provider of genomics-based information for transplant patients.
Our primary operations are in Brisbane, California; Omaha, Nebraska and Stockholm, Sweden.
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