CAMPHIGH SIGNALOPERATIONAL10-K

CAMP has shifted strategic focus to SYNGAP1 disorder treatment with lead candidate CMP-002, moving away from broader platform development while experiencing substantially higher operating losses.

The company appears to have narrowed its focus from a broad RNA platform approach to targeting a specific rare neurological disorder, suggesting a more defined development pathway but also increased concentration risk. The removal of language about multiple product candidates in varying stages suggests prioritization of resources around the SYNGAP1 program, which could accelerate development timelines but reduces pipeline diversity.

Comparing 2026-03-05 vs 2025-03-27View on EDGAR →
FINANCIAL ANALYSIS

CAMP's balance sheet strengthened significantly with cash and current assets growing roughly 70%, likely from fundraising activities, though stockholders' equity declined 25% due to dilution from new share issuances (outstanding shares increased from 20.1M to 51.9M). Operating performance deteriorated with net losses expanding substantially year-over-year, though operating cash flow improved modestly. The financial profile reflects a typical biotech capital raise to fund operations, but with meaningfully higher burn rates as the company advances its lead program.

FINANCIAL STATEMENT CHANGES
Current Assets
Balance Sheet
+71.9%
$66.4M$114.1M

Current assets grew 71.9% — improving short-term liquidity or inventory/receivables build.

Cash & Equivalents
Balance Sheet
+71%
$64.0M$109.5M

Cash position surged 71% — strong cash generation or capital raise providing significant financial cushion.

Current Liabilities
Balance Sheet
+61.6%
$9.6M$15.5M

Current liabilities surged 61.6% — significant near-term obligations; verify ability to meet short-term debt.

Net Income
P&L
-55.2%
-$51.8M-$80.4M

Net income declined 55.2% — review whether driven by operations, interest costs, or non-recurring items.

Total Assets
Balance Sheet
+50.4%
$78.3M$117.8M

Asset base grew 50.4% — expansion through organic growth, acquisitions, or capital deployment.

Capital Expenditure
Cash Flow
-36.7%
$441K$279K

Capex reduced 36.7% — investment cycle winding down or capital discipline; may improve near-term free cash flow.

Operating Cash Flow
Cash Flow
+35.1%
-$45.6M-$29.6M

Operating cash flow surged 35.1% — exceptional cash generation, highest quality earnings signal.

Stockholders Equity
Balance Sheet
-24.5%
$63.1M$47.7M

Equity decreased 24.5% — buybacks or losses reducing book value, monitor solvency ratios.

LANGUAGE CHANGES
NEW — 2026-03-05
PRIOR — 2025-03-27
ADDED
As of March 4, 2026, there were 51,919,321 shares of the registrant s common stock, par value $0.0001 per share, outstanding.
Our lead product candidate, CMP-002, has the potential to be the first disease-modifying therapy for the treatment of synaptic Ras GTPase activating protein 1 ( SYNGAP1 )-related disorder, or SYNGAP1, a severe developmental and epileptic encephalopathy ( DEE ) characterized by seizures, developmental delays, and cognitive impairments.
SYNGAP1 is caused by haploinsufficiency of the SYNGAP1 gene, where mutation of one gene copy results in a reduction in functional SYNGAP protein levels of up to 50%.
While we believe that it remains underdiagnosed, we estimate that there are approximately 21,000 individuals living with SYNGAP1 in the United States and the five largest European markets.
There are no approved disease-modifying therapies for SYNGAP1.
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REMOVED
As of March 13, 2025, there were 20,161,072 shares of the registrant s common stock, par value $0.0001 per share, outstanding.
Our product candidates are in varying stages of preclinical and clinical development and we have not completed a clinical trial of any product candidate.
If these third parties do not successfully carry out their contractual duties, fail to comply with applicable regulatory requirements, or do not meet expected deadlines, our development programs may be delayed or subject to increased costs or we may be unable to obtain regulatory approval for or commercialize our product candidates; Prior to the completion of our initial public offering, there was no public market for our common stock.
An active, liquid, and orderly market for our common stock may not develop or be sustained, or we may in the future fail to satisfy the continued listing requirements of Nasdaq; and The trading price of the shares of our common stock could be highly volatile, and purchasers of our common stock could incur substantial losses.
Regulatory RNAs ( regRNAs ), play a central role in the regulation of every protein-coding gene by contributing to gene activation and suppression.
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