ADPTHIGH SIGNALOPPORTUNITY10-K

ADPT demonstrated exceptional financial turnaround with 55% revenue growth and 65% reduction in operating losses while strategically refocusing its Immune Medicine business toward data-driven solutions.

The company's dramatic improvement across all financial metrics suggests successful execution of its 2024 reorganization strategy, with the MRD business driving substantial growth and improved operational efficiency. The strategic pivot from drug discovery to leveraging proprietary datasets (100k+ disease signatures, 5M+ TCR matches) positions ADPT as a valuable data platform company in the expanding immunology market, with total addressable market estimates increasing from $5.5B to $6.2B.

Comparing 2026-02-26 vs 2025-03-03View on EDGAR →
FINANCIAL ANALYSIS

ADPT delivered outstanding financial performance with revenue surging 55% to $277M while dramatically reducing losses - operating income improved 65% and net income improved 63% despite still being negative. The company strengthened its balance sheet with cash rising 47% to $70.5M, total liabilities declining 15%, and positive working capital trends including 21% growth in receivables supporting the revenue expansion. This represents a comprehensive financial turnaround indicating successful business transformation and improved operational leverage.

FINANCIAL STATEMENT CHANGES
Operating Income
P&L
+64.9%
-$162.5M-$57.1M

Operating leverage kicking in — revenue growth outpacing cost growth, a hallmark of scaling businesses.

Net Income
P&L
+62.7%
-$159.5M-$59.5M

Net income grew 62.7% — bottom-line growth signals improving overall business health.

Revenue
P&L
+54.8%
$179.0M$277.0M

Strong top-line growth of 54.8% — accelerating demand or successful expansion into new markets.

Operating Cash Flow
Cash Flow
+51.7%
-$95.2M-$46.0M

Operating cash flow surged 51.7% — exceptional cash generation, highest quality earnings signal.

Cash & Equivalents
Balance Sheet
+47.1%
$47.9M$70.5M

Cash position surged 47.1% — strong cash generation or capital raise providing significant financial cushion.

Accounts Receivable
Balance Sheet
+20.7%
$41.7M$50.4M

Receivables grew 20.7% — monitor days sales outstanding for collection efficiency.

Inventory
Balance Sheet
+16.4%
$8.4M$9.8M

Inventory built 16.4% — monitor whether demand supports this build or if write-downs may follow.

Total Liabilities
Balance Sheet
-14.6%
$336.9M$287.7M

Liabilities reduced 14.6% — deleveraging improves balance sheet strength and financial flexibility.

LANGUAGE CHANGES
NEW — 2026-02-26
PRIOR — 2025-03-03
ADDED
As of February 20, 2026, the Registrant had 153,981,561 shares of common stock, $0.0001 par value per share, outstanding.
In 2024, we reorganized our company around two main businesses: the MRD business, consisting of clinical assessment of minimal residual disease ( MRD ) in lymphoid malignancies, and Immune Medicine or the IM business, with a focus on creating applications and products based on unique capabilities to connect the adaptive immune response to disease.
We believe the total addressable market for the MRD business is approximately $6.2 billion, approximately $5.3 billion of which is derivable from clinical testing.
We have created a powerful data engine to improve our understanding of the immune system and address multiple immunology problems.
These proprietary datasets include more than 100,000 signatures of cancer and autoimmune disease and more than 5,000,000 matches of TCRs to disease-related antigens.
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REMOVED
As of February 26, 2025, the Registrant had 148,582,201 shares of common stock, $0.0001 par value per share, outstanding.
In 2024, we reorganized our company around two main businesses: the "MRD business," consisting of clinical assessment of minimal residual disease ( MRD ) in lymphoid malignancies, and "Immune Medicine" or the "IM business," built on drug discovery and development driven by immune medicine.
We believe the total addressable market for the MRD business is approximately $5.5 billion, approximately $4.8 billion of which is derivable from clinical testing.
The IM business focuses on the discovery and development of transformative immune-based therapies in the treatment of patients with cancer and autoimmune diseases.
Our strategic priorities in the IM business include supporting our partner, Genentech, Inc.
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