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PTGX Insider Trading & Form 4 Activity

Protagonist Therapeutics, Inc
Last filing: Jun 25, 2026·13 days ago
BEARISH · LAST 90 DAYS
0%
buyers
$0
0 buys
$13.4M
5 sells
-$13.4M
net selling
2
insiders
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Net flow — last 12 months

Monthly net of insider buys minus sells. Green months indicate net buying; red months indicate net selling.

Most active insiders

Ranked by total transaction value over the last 90 days.

INSIDERBOUGHTSOLDNET
Patel Dinesh V Ph D
President and CEO
$15.0M
-$15.0M
Giraudo Bryan
Insider
$5.9M
-$5.9M
Waddill William D.
Insider
$2.9M
-$2.9M

Recent transactions

Every Form 4 transaction for PTGX, newest first.

EXERCISE10b5-1
Waddill William D. · Insider
Tx Jun 23·Filed Jun 25·EDGAR ↗
9,000 sh @ $16.54
$149K
SELL10b5-1
Waddill William D. · Insider
Tx Jun 23·Filed Jun 25·EDGAR ↗
9,000 sh @ $117.94
$1.1M
EXERCISE10b5-1
Waddill William D. · Insider
Tx Jun 10·Filed Jun 11·EDGAR ↗
3,000 sh @ $11.80
$35K
SELL10b5-1
Waddill William D. · Insider
Tx Jun 10·Filed Jun 11·EDGAR ↗
9,000 sh @ $107.68
$969K
EXERCISE10b5-1
Waddill William D. · Insider
Tx Jun 10·Filed Jun 11·EDGAR ↗
6,000 sh @ $16.54
$99K
SELL10b5-1
Waddill William D. · Insider
Tx May 29·Filed Jun 1·EDGAR ↗
9,000 sh @ $99.64
$897K
EXERCISE10b5-1
Waddill William D. · Insider
Tx May 29·Filed Jun 1·EDGAR ↗
9,000 sh @ $11.80
$106K
EXERCISE10b5-1
Patel Dinesh V Ph D · President and CEO
Tx May 12·Filed May 14·EDGAR ↗
75,000 sh @ $21.58
$1.6M
SELL10b5-1
Patel Dinesh V Ph D · President and CEO
Tx May 12·Filed May 14·EDGAR ↗
75,000 sh @ $100.12
$7.5M
SELL
Patel Dinesh V Ph D · President and CEO
Tx May 12·Filed May 12·EDGAR ↗
75,000 sh @ $100.12
$7.5M
EXERCISE
Patel Dinesh V Ph D · President and CEO
Tx May 12·Filed May 12·EDGAR ↗
75,000 sh @ $21.58
$1.6M
SELL
Giraudo Bryan · Insider
Tx May 8·Filed May 11·EDGAR ↗
5,130 sh @ $100.00
$513K
SELL
Giraudo Bryan · Insider
Tx May 8·Filed May 11·EDGAR ↗
6,000 sh @ $100.00
$600K
SELL
Giraudo Bryan · Insider
Tx May 7·Filed May 11·EDGAR ↗
12,000 sh @ $100.07
$1.2M
SELL
Giraudo Bryan · Insider
Tx May 7·Filed May 11·EDGAR ↗
36,000 sh @ $100.14
$3.6M
EXERCISE
Giraudo Bryan · Insider
Tx May 7·Filed May 11·EDGAR ↗
12,000 sh @ $6.98
$84K
EXERCISE
Giraudo Bryan · Insider
Tx May 7·Filed May 11·EDGAR ↗
24,000 sh @ $6.45
$155K

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About PTGX insider trading data

Form 4 is the SEC filing required when an officer, director, or 10% owner of a public company buys or sells the company's stock. By law, these filings must be submitted within two business days of the trade. Tracenotes pulls every Form 4 filing for PTGX from EDGAR, parses it, and surfaces the activity on this page.

What insider buying tells you. Open-market purchases by insiders are widely studied as a meaningful signal. Unlike stock awards (which are compensation, not conviction), an executive spending their own money to buy shares of the company they run is a vote of confidence. Studies have found insider-buying clusters — three or more insiders buying within a short window — outperform the broader market over the following year.

What insider selling tells you. Selling is noisier. Many sales are pre-scheduled under SEC Rule 10b5-1 plans, which let insiders sell on a fixed schedule regardless of company news. We label these "10b5-1" so you can see them. Discretionary sales — sales not tied to a plan — are more meaningful, especially when multiple insiders sell in quick succession.

Tracenotes methodology. We scan EDGAR daily for new Form 4 filings, parse them into individual transactions, and detect clusters when three or more distinct insiders buy or sell within a 14-day window. The data on this page covers the last 12 months. For deeper analysis, Tracenotes also runs language-change detection on 10-K and 10-Q filings — that's our core product.

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Frequently asked questions

What is a Form 4 filing?

Form 4 is the SEC disclosure required when a company insider — an officer, director, or 10% owner — buys or sells the company's stock. By law these filings must be submitted within two business days of the trade.

Is insider buying PTGX always bullish?

Open-market purchases by insiders are widely viewed as a bullish signal because executives are spending their own money. Stock awards and option exercises are part of compensation and don't carry the same weight, which is why we treat them separately on this page.

What is a 10b5-1 trade?

A trade made under SEC Rule 10b5-1, which lets insiders pre-schedule sales weeks or months in advance. These sales execute on a fixed plan regardless of company news, so they're a weaker signal than discretionary sales. We label them with a "10b5-1" tag.

What is an insider cluster?

A cluster is when three or more distinct insiders buy or sell within a 14-day window. Clusters are studied as stronger signals than single trades because multiple people independently reach the same view. We surface active clusters on Protagonist Therapeutics, Inc (PTGX) when they form.

Where does PTGX insider trading data come from?

Every Form 4 filing for PTGX is sourced directly from SEC EDGAR. Tracenotes scans EDGAR daily, parses each Form 4 into individual transactions, and updates this page within hours of new filings.

Nothing on this page constitutes investment advice. Form 4 data is sourced from SEC EDGAR and provided for research purposes only.

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